Aberrant crypt foci as biomarkers for colonic dysplasia
Aberrant crypt foci as biomarkers for colonic dysplasia
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DOI：
10.1038/ncpgasthep0256
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发表时间：
2005-09-01
期刊：
影响因子：
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通讯作者：
Adler, DG
中科院分区：
文献类型：
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作者：
Adler, DG
背景：异常隐窝病灶（ACF）的患病率已显示出从健康受试者到外生性腺瘤或癌症患者呈上升趋势。尚未进行研究来评估这种趋势是否适用于平坦型或凹陷型结直肠肿瘤患者。目的量化并比较健康人与扁平型或凹陷型结直肠肿瘤患者直肠ACF的患病率。
BackgroundThe prevalence of aberrant crypt foci (ACF) has been shown to follow an increasing trend from healthy subjects to patients with exophytic adenomas or cancers. Studies have not been performed to assess whether this trend is true for patients with flat or depressed colorectal neoplasia.ObjectiveTo quantify and compare the prevalence of rectal ACF in healthy subjects and patients with flat or depressed colorectal neoplasia.