Exploring Tai Chi Exercise and Mind-Body Breathing in Patients with COPD in a Randomized Controlled Feasibility Trial.

Exploring Tai Chi Exercise and Mind-Body Breathing in Patients with COPD in a Randomized Controlled Feasibility Trial.
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在随机对照可行性试验中探索慢性阻塞性肺病患者的太极运动和​​身心呼吸。

DOI:
10.1080/15412555.2021.1928037
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发表时间:
2021-06
期刊:
影响因子:
2.2
通讯作者:
Yeh GY
Yeh GY
中科院分区:
医学4区
文献类型:
--
作者:
Kraemer KM;Litrownik D;Moy ML;Wayne PM;Beach D;Klings ES;Reyes Nieva H;Pinheiro A;Davis RB;Yeh GY

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在这项试点可行性随机对照试验中,中度至重度COPD患者被随机分为12周太极或MBB干预组。在基线、12周和24周时对参与者进行评估。通过干预依从性评估的可行性是主要结局。我们还初步估计了COPD症状、健康相关生活质量、认知情绪功能和功能状态在基线、12周和24周三个时间点上的组间差异。共有92名参与者被2:1随机分配到太极组(n = 61)或MBB组(n = 31)。前12周,太极拳组的整体坚持度为62%,MBB组为75%。从基线到12周,太极表现出更大的抑郁症状改善(科恩效应量(ES) = - 0.53;adj mean diff = - 2.31[- 5.7, 1.07])、6分钟步行测试距离(ES = .47; adj mean diff = 62.04[2.85, 121.22])、社会支持(ES = .36; adj mean diff = .19[- 0.11, 0.49])和椅架(ES = .44; adj mean diff = .91[- 0.05, 1.86])。在24周的随访中,只有社会支持得到了改善。太极拳和MBB对慢性阻塞性肺病患者是可行的。初步结果表明,虽然我们的正念呼吸干预可能不足以影响结果,但太极拳可能会在情绪、社会支持和功能能力方面带来短期好处。需要做更多的工作来更好地理解正念呼吸对慢性阻塞性肺病的影响,并研究长期保持太极拳改善的方法。
In this pilot feasibility randomized controlled trial, participants with moderate to severe COPD were randomized to a 12-week tai chi or MBB intervention. Participants were assessed at baseline, 12 weeks, and 24 weeks. Feasibility, as assessed by intervention adherence, was the primary outcome. We also estimated preliminary between-group differences in COPD symptoms and health-related quality of life, cognitive-emotional function, and functional status across three timepoints: baseline, 12, and 24 weeks. A total of 92 participants were randomized 2:1 to tai chi (n = 61) or MBB (n = 31). The overall group adherence in the first 12 weeks was 62% in tai chi and 75% in MBB. From baseline to 12 weeks, tai chi demonstrated greater improvements in depressive symptoms (Cohen’s d effect size (ES) = −.53; adj mean diff = −2.31 [−5.7, 1.07]), 6-minute walk test distance (ES = .47; adj mean diff = 62.04 [2.85, 121.22]), social support (ES = .36; adj mean diff = .19 [−0.11, 0.49]) and chair stand (ES = .44; adj mean diff = .91 [−0.05, 1.86]). Only improvements in social support were maintained at 24-week follow-up. Tai chi and MBB are feasible for individuals with COPD. Preliminary effects suggest that while our mindful breathing intervention may not be sufficient to impact outcomes, tai chi may result in short-term benefits in mood, social support and functional capacity. More work is needed to better understand mindful breathing for COPD and to examine methods for maintaining improvements from tai chi over time.
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