RETINAL STRUCTURAL CHANGES ASSOCIATED WITH RETINAL ARTERIAL MACROANEURYSM EXAMINED WITH OPTICAL COHERENCE TOMOGRAPHY
RETINAL STRUCTURAL CHANGES ASSOCIATED WITH RETINAL ARTERIAL MACROANEURYSM EXAMINED WITH OPTICAL COHERENCE TOMOGRAPHY
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DOI：
10.1097/iae.0b013e3181a2f26a
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发表时间：
2009-06-01
影响因子：
3.3
通讯作者：
Yoshimura, Nagahisa
中科院分区：
文献类型：
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作者：
Tsujikawa, Akitaka;Sakamoto, Atsushi;Yoshimura, Nagahisa
目的：研究视网膜动脉巨大动脉瘤相关的视网膜结构变化及其与视力预后的关系。方法：我们回顾性研究了44例44眼视网膜动脉巨大动脉瘤患者的病历资料，所有患者均表现出出血性和/或渗出性改变的中心凹视力障碍。结果：30只眼（68%）首次就诊时出现严重出血并发症。在中心凹下视网膜下出血的眼睛中，视网膜结构在初次就诊时相对保留。然而，在最后一次访视时，中心凹结构往往退化，特别是在其外部方面，视力恢复有限。出血并发症轻微的14只眼（32%）表现为动脉瘤引起的广泛渗出性改变。其中13只眼，OCT检查显示广泛的视网膜水肿，主要在外层视网膜。12眼因中心凹下视网膜水肿引起局灶性浆液性视网膜脱离。8眼广泛渗出性改变显示硬渗出物在黄斑区的积累，这些眼睛的视力恢复往往是limited.Conclusion：视网膜下出血或广泛渗出性改变，从视网膜动脉大动脉瘤可导致破坏中心凹外感光层，导致视力不良的结果。视网膜29：782-792，2009
Purpose: To study the retinal structural changes associated with a retinal arterial macroaneurysm and their association with visual prognosis.Methods: We studied retrospectively the medical records of 44 eyes of 44 patients with a retinal arterial macroaneurysm; all eyes showed hemorrhagic and/or exudative changes of the fovea with a visual disturbance. The retinal structural changes were examined by optical coherence tomography (OCT).Results: At the initial visit, 30 eyes (68%) showed severe hemorrhagic complications. In eyes with subretinal hemorrhage beneath the fovea, retinal structure was relatively preserved at the initial visit. At the final visit, however, foveal structure was often degenerated, especially in its outer aspect, with limited visual recovery. The 14 eyes (32%) with minimal hemorrhagic complications showed an extensive exudative change caused by the aneurysm. In 13 of these eyes, OCT examination revealed extensive retinal edema, predominantly in the outer retina. Retinal edema beneath the fovea caused a focal serous retinal detachment in 12 eyes. Eight eyes with extensive exudative change showed an accumulation of hard exudates in the macular area, and visual recovery of these eyes was often limited.Conclusion: Subretinal hemorrhage or extensive exudative change from a retinal arterial macroaneurysm can cause destruction of the foveal outer photoreceptor layer, resulting in a poor visual outcome. RETINA 29:782-792, 2009