Waning Vaccine Effectiveness Against Influenza-Associated Hospitalizations Among Adults, 2015-2016 to 2018-2019, United States Hospitalized Adult Influenza Vaccine Effectiveness Network
Waning Vaccine Effectiveness Against Influenza-Associated Hospitalizations Among Adults, 2015-2016 to 2018-2019, United States Hospitalized Adult Influenza Vaccine Effectiveness Network
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DOI：
10.1093/cid/ciab045
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发表时间：
2021-01-19
影响因子：
11.8
通讯作者：
Patel, Manish
中科院分区：
文献类型：
--
作者：
Ferdinands, Jill M.;Gaglani, Manjusha;Patel, Manish
我们观察到，随着接种疫苗后预防甲型流感 (H3N2)、甲型流感 (H1N1)pdm09 和成人乙型流感/山形相关住院的疫苗接种时间的增加，流感疫苗的有效性下降。接种疫苗后不久即可观察到最大疫苗效力 (VE)，随后疫苗接种后每月 VE 绝对值下降约 8%-9%。
We observed decreased effectiveness of influenza vaccine with increasing time since vaccination for prevention of influenza A(H3N2), influenza A(H1N1)pdm09, and influenza B/Yamagata-associated hospitalizations among adults. Maximum vaccine effectiveness (VE) was observed shortly after vaccination, followed by an absolute decline in VE of about 8%-9% per month postvaccination.