A General Copper Catalyst for Photoredox Transformations of Organic Halides
A General Copper Catalyst for Photoredox Transformations of Organic Halides
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DOI：
10.1021/acs.orglett.7b01518
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发表时间：
2017-07-07
期刊：
影响因子：
5.2
通讯作者：
Evano, Gwilherm
中科院分区：
文献类型：
--
作者：
Michelet, Bastien;Deldaele, Christopher;Evano, Gwilherm
报道了一种广泛应用于有机卤化物光氧化还原转化的铜催化剂。在[DPEphos)(bcp)Cu]PF6和一种胺的催化量下，在可见光照射下，一系列未活化的芳基和烷基卤化物通过罕见的Ch(I)/Cu(I)*/Cu(0)催化循环被顺利活化。该配合物能有效催化一系列自由基反应，包括芳烃的还原、环化和直接芳基化。
A broadly applicable copper catalyst for photoredox transformations of organic halides is reported. Upon visible light irradiation in the presence of catalytic amounts of [DPEphos)(bcp)Cu]PF6 and an amine, a range of unactivated aryl and alkyl halides were shown to be smoothly activated through a rare Ch(I)/Cu(I)*/Cu(0) catalytic cycle. This complex efficiently catalyzes a series of radical processes, including reductions, cyclizations, and direct arylation of arenes.