Impaired peripheral somatosensory function in children with Down syndrome
Impaired peripheral somatosensory function in children with Down syndrome
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DOI：
10.1055/s-2007-979780
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发表时间：
1995-12-01
期刊：
影响因子：
1.4
通讯作者：
Rosen, I
中科院分区：
文献类型：
--
作者：
Brandt, BR;Rosen, I
对6例11-16岁唐氏综合征（DS）患儿和10例年龄相仿的健康对照者进行双侧正中神经感觉神经造影。DS组拇指和第3指的感觉神经传导速度明显低于正常。感觉神经动作电位在DS儿童中也较低，并且在拇指刺激后差异特别明显。使用头皮电极的感觉诱发电位记录在5个DS儿童和所有控制。DS组与对照组比较无明显差异。有人建议，外周躯体感觉功能受损应添加到以前已知的症状构成DS。结果可能有助于以前的研究结果，DS儿童在触觉感知测试中表现不佳。
Sensory neurography of the median nerve was performed bilaterally in 6 children with Down syndrome (DS) aged 11-16 years and in 10 healthy controls of similar age. The sensory nerve conduction velocities from the thumbs and 3rd fingers were recorded and were significantly subnormal in the DS group. Sensory nerve action potentials were also lower in the DS children and the difference was particularly evident following stimuli of the thumbs. Using scalp electrodes sensory evoked potential latencies were recorded in five of the DS children and all controls. There was no obvious difference between the subjects with DS and the controls. It is suggested that an impaired peripheral somatosensory function should be added to previously known symptoms constituting DS. The results may contribute to previous findings of a poor performance of DS children in tests of tactual perception.