Coronary artery bypass graft surgery outcomes in the United States: Impact of the coronavirus disease 2019 (COVID-19) pandemic.
Coronary artery bypass graft surgery outcomes in the United States: Impact of the coronavirus disease 2019 (COVID-19) pandemic.
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DOI：
10.1016/j.xjon.2021.03.016
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发表时间：
2021-06
期刊：
影响因子：
--
通讯作者：
Arora P
中科院分区：
文献类型：
--
作者：
Parcha V;Kalra R;Glenn AM;Davies JE;Kuranz S;Arora G;Arora P
2019冠状病毒病（COVID-19）大流行爆发后，美国接受紧急及常规心血管护理的患者大幅减少。我们试图评估于二零二零年COVID-19疫情期间接受冠状动脉旁路移植术（CABG）手术的患者的不良临床结果风险，并将风险与二零一九年疫情前接受CABG的患者进行比较。对TriNetX研究网络数据库进行了回顾性横断面分析。2019年1月20日至2019年9月15日期间接受CABG的患者纳入2019年队列，2020年1月20日至2020年9月15日期间接受CABG的患者纳入2020年队列。进行倾向评分匹配，并评估30天内发生死亡率、急性肾损伤、卒中、急性呼吸窘迫综合征和机械通气的几率。2020年接受CABG的患者数量从2019年的5534例下降至2020年的3569例，下降了35. 5%。在倾向评分匹配后，在2019年和2020年队列中确定了3569对患者。与2019年接受CABG的患者相比，2020年接受CABG的患者30天死亡率为0.96（95%置信区间[CI]，0.69-1.33; P = 0.80）。中风的几率（比值比[OR]，1.201; 95% CI，0.96-1.39），急性肾损伤（OR，0.76; 95%CI，0.59-1.08），急性呼吸窘迫综合征（OR，1.01; 95% CI，0.60-2.42）和机械通气（OR，1.11; 95% CI，0.94-1.30）在2个队列之间相似。二零二零年接受冠状动脉旁路移植术的患者人数较二零一九年大幅下降。与2019年相比，在COVID-19背景下接受CABG的患者出现不良临床结局的几率相似。
There has been a substantial decline in patients presenting for emergent and routine cardiovascular care in the United States after the onset of the coronavirus disease 2019 (COVID-19) pandemic. We sought to assess the risk of adverse clinical outcomes among patients undergoing coronary artery bypass graft (CABG) surgery during the 2020 COVID-19 pandemic period and compare the risks with those undergoing CABG before the pandemic in the year 2019. A retrospective cross-sectional analysis of the TriNetX Research Network database was performed. Patients undergoing CABG between January 20, 2019, and September 15, 2019, contributed to the 2019 cohort, and those undergoing CABG between January 20, 2020, and September 15, 2020, contributed to the 2020 cohort. Propensity-score matching was performed, and the odds of mortality, acute kidney injury, stroke, acute respiratory distress syndrome, and mechanical ventilation occurring by 30 days were evaluated. The number of patients undergoing CABG in 2020 declined by 35.5% from 5534 patients in 2019 to 3569 patients in 2020. After propensity-score matching, 3569 patient pairs were identified in the 2019 and the 2020 cohorts. Compared with those undergoing CABG in 2019, the odds of mortality by 30 days were 0.96 (95% confidence interval [CI], 0.69-1.33; P = .80) in those undergoing CABG in 2020. The odds for stroke (odds ratio [OR], 1.201; 95% CI, 0.96-1.39), acute kidney injury (OR, 0.76; 95% CI, 0.59-1.08), acute respiratory distress syndrome (OR, 1.01; 95% CI, 0.60-2.42), and mechanical ventilation (OR, 1.11; 95% CI, 0.94-1.30) were similar between the 2 cohorts. The number of patients undergoing CABG in 2020 has substantially declined compared with 2019. Similar odds of adverse clinical outcomes were seen among patients undergoing CABG in the setting of COVID-19 compared with those in 2019.
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影响因子：
9.6
作者：
Parcha V;Kalra R;Bhatt SP;Berra L;Arora G;Arora P
通讯作者：
Arora P
影响因子：
2.8
作者：
Sobolev BG;Fradet G;Hayden R;Kuramoto L;Levy AR;FitzGerald MJ
通讯作者：
FitzGerald MJ
影响因子：
8.9
作者：
Alkhouli, Mohamad;Nanjundappa, Aravinda;Bhatt, Deepak L.
通讯作者：
Bhatt, Deepak L.
影响因子：
5.4
作者：
Patel V;Jimenez E;Cornwell L;Tran T;Paniagua D;Denktas AE;Chou A;Hankins SJ;Bozkurt B;Rosengart TK;Jneid H
通讯作者：
Jneid H
影响因子：
15.8
作者：
Harrison, Stephanie L.;Fazio-Eynullayeva, Elnara;Lip, Gregory Y. H.
通讯作者：
Lip, Gregory Y. H.