Rapid and Accurate Left Ventricular Chamber Quantification Using a Novel CMR Segmentation Algorithm: A Clinical Validation Study

Rapid and Accurate Left Ventricular Chamber Quantification Using a Novel CMR Segmentation Algorithm: A Clinical Validation Study
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DOI:
10.1002/jmri.22080
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发表时间:
2010-04-01
影响因子:
4.4
通讯作者:
Weinsaft, Jonathan W.
Weinsaft, Jonathan W.
中科院分区:
医学2区
文献类型:
--
作者:
Codella, Noel C. F.;Cham, Matthew D.;Weinsaft, Jonathan W.

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目的:评估一种不涉及几何假设的新型自动左心室 (LV) 分割算法 (LV-METRIC) 的临床表现。材料和方法:独立使用 LV-METRIC 和手动追踪 (MT) 来量化 151 名接受电影 CMR(稳态自由进动)的连续患者的 LV 体积和 LVEF(射血分数)。使用相差成像独立测量每搏输出量。结果:LV-METRIC 在所有病例中均成功。平均 LVEF 与 MT 相差 1 点以内(Delta 0.6 +/- 2.3%。P < 0.05),患有晚期收缩功能障碍 (LVEF) 的患者 (0.5 +/- 2.5%) 与不患有晚期收缩功能障碍 (LVEF) 的患者 (0.9 +/- 2.3%;P = 0.01) 之间的差异较小
Purpose: To evaluate the clinical performance of a novel automated left ventricle (LV) segmentation algorithm (LV-METRIC) that involves no geometric assumptions.Materials and Methods: LV-METRIC and manual tracing (MT) were used independently to quantify LV volumes and LVEF (ejection fraction) for 151 consecutive patients who underwent cine-CMR (steady-state free precession). Phase contrast imaging was used to independently measure stroke volume.Results: LV-METRIC was successful in all cases. Mean LVEF was within 1 point of MT (Delta 0.6 +/- 2.3%. P < 0.05), with smaller differences among patients with (0.5 +/- 2.5%) versus those without (0.9 +/- 2.3%; P = 0.01) advanced systolic dysfunction (LVEF