Investigation of different approaches to reduce allergens in asthmatic children's homes - The Breath of Fresh Air Project, Cornwall, United Kingdom
Investigation of different approaches to reduce allergens in asthmatic children's homes - The Breath of Fresh Air Project, Cornwall, United Kingdom
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DOI：
10.1016/j.scitotenv.2011.06.011
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发表时间：
2011-09-01
影响因子：
9.8
通讯作者：
Richardson, George
中科院分区：
文献类型：
--
作者：
Eick, Susan Ann;Richardson, George
在2001年至2004年期间，进行了一项研究，以评估在哮喘儿童家中安装减少过敏原的干预措施对室内环境和健康的影响。根据试点研究的结果，以确定一种干预措施，将提供改善的症状评分和减少屋尘螨过敏原（Der p 1），机械通风和热回收（MVHR）系统安装在16个家庭。在安装MVHR系统之前和之后进行了环境和呼吸健康评估。结果表明，MVHR系统的安装降低了客厅地毯和床垫中的Der p 1浓度。运动时呼吸困难、喘息和白天和夜间咳嗽的症状评分显著降低。虽然主研究没有平行对照组，但初步研究对照组（未接受干预）缺乏变化，表明症状评分的变化部分与干预有关。需要更大规模的试验来确定MVHR系统在家庭中改善室内空气质量和减少哮喘症状的功效。(C)2011爱思唯尔有限公司版权所有。
During 2001 to 2004, a study was conducted to assess the indoor environmental and health impact of installing allergen-reducing interventions in the homes of asthmatic children. Based on the results of a pilot study, to determine an intervention that would provide improved symptom scores and a reduction in house dust mite allergen (Der p 1), mechanical ventilation and heat recovery (MVHR) systems were installed in 16 homes. Environmental and respiratory health assessments were conducted before and after the installation of the MVHR systems. The results indicated that the installation of MVHR systems reduced Der p 1 concentrations in living room carpets and mattresses. There were significant reductions in symptom scores for breathlessness during exercise, wheezing, and coughing during the day and night. Although, there was not a parallel control group for the main study, the lack of change in the pilot study control group (who did not receive an intervention), indicated that the changes in symptom scores were in part to do with the intervention. Larger scale trials are needed to determine the efficacy of MVHR systems in homes to improve indoor air quality and reduce asthma symptoms. (C) 2011 Elsevier B.V. All rights reserved.