Psychotic-like experiences in childhood and early adolescence: Clarifying the construct and future directions.

Psychotic-like experiences in childhood and early adolescence: Clarifying the construct and future directions.
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童年和青春期早期的类似精神病的经历:澄清结构和未来的方向。

DOI:
10.1016/j.schres.2022.06.030
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发表时间:
2022
影响因子:
4.5
通讯作者:
Karcher,NicoleR
Karcher,NicoleR
中科院分区:
医学2区
文献类型:
--
作者:
Karcher,NicoleR

文献摘要

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类精神病经历(ple),也被称为精神病经历或亚临床精神病症状,包括不寻常的思想内容和知觉体验,与精神病症状相比不那么严重(图1a)。尽管ple通常被定义为无论年龄大小都属于同一个连续体,但与后期的ple相比,关于童年和青春期早期这些经历的讨论要少得多。大约22%-60%的年轻人经历过某种形式的ple (Karcher等人,2018;Kelleher等人,2012),假设高患病率源于较年轻的ple往往表现出较低的严重程度,较高的假阳性率,并且与典型发展有较大的重叠。尽管ple可能与某些人没有特别的临床相关性,但对于很大一部分青少年来说,这些经历要么与痛苦有关(~ 43% - 46%)(Karcher等人,2018;Moriyama等人,2019)和/或随后在青春期或成年期发展为可诊断的心理健康问题(~ 57% - 92%)(Fisher等人,2013;Kelleher等人,2012)。尽管在过去的几年里,我们对青少年期ple的理解有所增加,但目前的评论旨在澄清有关儿童期中期和青春期早期ple的概念化和临床相关性的问题,并讨论潜在的未来方向,包括识别青少年恶化ple的风险。
Psychotic-like experiences (PLEs), also known as psychotic experiences or subclinical psychotic symptoms, include unusual thought content and perceptual experiences that are less severe compared to psychotic disorder symptoms (Fig. 1 a). While PLEs are often conceptualized as belonging on the same continuum regardless of age, there has been a lot less discussion of these experiences in childhood and early adolescence compared to PLEs at later ages. Approximately 22%–60% of youth experience some form of PLEs (Karcher et al., 2018; Kelleher et al., 2012), with high prevalence rates hypothesized to stem from PLEs in younger ages frequently showing lower severity, higher false positives rates, and greater overlap with typical development. Although PLEs may not be particularly clinically relevant for some, for a large subset of youth these experiences are either associated with distress (~ 43–46%)(Karcher et al., 2018; Moriyama et al., 2019) and/or subsequent development of diagnosable mental health concerns in adolescence or adulthood (~ 57–92%)(Fisher et al., 2013; Kelleher et al., 2012). Although our understanding of PLEs in youth has increased over the past several years, the current commentary aims to clarify questions regarding the conceptualization and clinical relevance of PLEs in middle childhood and early adolescence, as well as discuss potential future directions including identification of youth at-risk for worsening PLEs.