LACTOBACILLUS-PLANTARUM, AN ORGANISM NOT REQUIRING IRON
LACTOBACILLUS-PLANTARUM, AN ORGANISM NOT REQUIRING IRON
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DOI：
10.1111/j.1574-6968.1983.tb00504.x
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发表时间：
1983-01-01
影响因子：
2.1
通讯作者：
ARCHIBALD, F
中科院分区：
文献类型：
--
作者：
ARCHIBALD, F
铁是各种基本生化机制所需的辅助因子，因此人们普遍认为所有生物体都对金属有绝对需求[1]。近年来，由于已证明的复杂的Fe获取机制[2]，以及越来越多的证据表明获取宿主Fe的能力是许多微生物病原体的毒力因子[3]，对Fe在生物系统中的获取和作用的兴趣一直很高。在研究植物乳杆菌中的氧毒性和锰的作用的过程中，生物体的细胞内铁浓度和营养铁的需求进行了简要评估，并发现无法检测的方法采用[4]。由于完全缺乏铁的需求将是生物学上独特的，可能对理解生物体不寻常的氧解毒机制很重要[4，5]，因此进行了本研究。
Iron is a required co-factor for such a variety of basic biochemical mechanisms that it is generally accepted that all living organisms have an absolute requirement for the metal [1]. Interest in the acquisition and role of Fe in biological systems has been high in recent years due both to the sophisticated Fe acquisition mechanisms demonstrated [2], and to mounting evidence that the ability to acquire host Fe is a virulence factor for many microbial pathogens [3].In the course of investigations on oxygen toxicity and the role of manganese in Lactobacillus plantarum, the organism's intracellular Fe concentration and nutritional Fe requirements were briefly assessed and found to be undetectable by the methods employed [4]. As complete lack of an Fe requirement would be both biologically unique and probably important in understanding the organism's unusual oxygen detoxifying mechanisms [4, 5], the present study was performed.