Supplementary motor area activation preceding voluntary movement is detectable with a whole-scalp magnetoencephalography system
Supplementary motor area activation preceding voluntary movement is detectable with a whole-scalp magnetoencephalography system
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DOI：
10.1006/nimg.2000.0579
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发表时间：
2000-06-01
期刊：
影响因子：
5.7
通讯作者：
Deecke, L
中科院分区：
文献类型：
--
作者：
Erdler, M;Beisteiner, R;Deecke, L
尽管关于辅助运动区（SIMA）的结构和功能的知识正在稳步增加，但 SMA 在人脑中的作用，例如 SMA 对 Bereitschafts 电位的贡献仍然不清楚且存在争议。本研究的目的是通过利用全头皮脑磁图 (MEG) 系统增加的空间信息进一步促进这一讨论，使我们能够记录 Bereitschaftspottial 1、Bereitschaftsfeld 1 (BF 1) 或准备区域 1 的磁当量。五名受试者执行了一项复杂的任务，一名受试者执行了简单的手指敲击任务。可以记录所有受试者的 BF 1。 BF 1 的首次出现发生在运动开始前的 -1.9 至 -1.7 秒范围内，执行简单任务的受试者除外（-1 秒）。对磁场分布和通道波形发展的分析表明，Bereitschaftsfeld 2 (BF 2) 或就绪场 2 在运动开始前约 -0.5 秒开始。在 BF 1 的时间范围内，偶极源分析仅将源定位在 SIMA 中，而还包含 BF 2 的时间范围的偶极源分析产生了偶极模型，包括初级运动区中的偶极。总之，通过全头 MEG 系统，首次可以用 MEG 检测健康受试者的 SMA 活动。 (C) 2000 年学术出版社。
Despite the fact that the knowledge about the structure and the function of the supplementary motor area (SIMA) is steadily increasing, the role of the SMA in the human brain, e,g., the contribution of the SMA to the Bereitschaftspotential, still remains unclear and controversial. The goal of this study was to contribute further to this discussion by taking advantage of the increased spatial information of a whole-scalp magnetoencephalography (MEG) system enabling us to record the magnetic equivalent of the Bereitschaftspotential 1, the Bereitschaftsfeld 1 (BF 1) or readiness field 1, Five subjects performed a complex, and one subject a simple, finger-tapping task. It was possible to record the BF 1 for all subjects. The first appearance of the BF 1 was in the range of -1.9 to -1.7 s prior to movement onset, except for the subject performing the simple task (-1 s). Analysis of the development of the magnetic field distribution and the channel waveforms showed the beginning of the Bereitschaftsfeld 2 (BF 2) or readiness field 2 at about -0.5 s prior to movement onset. In the time range of BF 1, dipole source analysis localized the source in the SIMA only, whereas dipole source analysis containing also the time range of BF 2 resulted in dipole models, including dipoles in the primary motor area. In summary, with a whole-head MEG system, it was possible for the first time to detect SMA activity in healthy subjects with MEG. (C) 2000 Academic Press.