LATENCY AND AMPLITUDE CHANGES IN ACOUSTIC STARTLE REFLEX OF RAT PRODUCES BY VARIATION IN AUDITORY PRESTIMULATION
LATENCY AND AMPLITUDE CHANGES IN ACOUSTIC STARTLE REFLEX OF RAT PRODUCES BY VARIATION IN AUDITORY PRESTIMULATION
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DOI：
10.1016/0031-9384(73)90185-6
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发表时间：
1973-01-01
影响因子：
2.9
通讯作者：
HAMMOND, GR
中科院分区：
文献类型：
--
作者：
ISON, JR;MCADAM, DW;HAMMOND, GR
两个实验研究了听觉前刺激（S1）对强张力爆发（S2）惊吓反射的振幅和潜伏期的影响。在第一项研究中，具有固定的s1强度，具有非常短（<15 msec）的ISIs反射幅度增加并且潜伏期通过s1的存在而减少，并且具有更长的间隔（大于或等于40 msec）的幅度减少并且潜伏期增加。抑制作用在滞后时间的幅度测量上是明显的，对改变潜伏期测量无效。在第二组中，当s1持续时间固定且较长时，反射振幅随着s1强度的增加而增加，达到中等（≈75 db）水平，但s1的进一步增加会导致振幅降低。然而，任何超过最小测试值（60 db）的s1强度的增加都会导致反射潜伏期的增加。这些实验揭示了听觉刺激对大鼠声惊吓反射的三种可分离的影响。
Two experiments investigated the effect of an auditory prestimulus (S1) on the amplitude and latency of the startle reflex to an intense tone burst (S2). In the first, with a fixed S1intensity, with very short (<15 msec) ISIs reflex amplitudes were increased and latencies reduced by S1presence and with longer intervals (⩾40 msec) amplitudes were reduced and latencies increased. Inhibition was apparent on the amplitude measure at lag times ineffective in altering the latency measure. In the second, with a fixed and long S1duration reflex amplitudes increased with an increase in S1intensity up to moderate (≈75 db) levels, but further increases in S1produced a reduction in amplitudes. However any increase in S1intensity over the minimum value tested (60 db) resulted in an increment in reflex latency. These experiments reveal the presence of three separable influences of auditory prestimuli on the acoustic startle reflex in the rat.