Nanoemulsions versus microemulsions: terminology, differences, and similarities
Nanoemulsions versus microemulsions: terminology, differences, and similarities
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DOI：
10.1039/c2sm06903b
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发表时间：
2012-01-01
期刊：
影响因子：
3.4
通讯作者：
McClements, David Julian
中科院分区：
文献类型：
--
作者：
McClements, David Julian
基于微乳液或纳米乳液的胶体递送系统越来越多地用于食品和制药工业中以包封、保护和递送亲脂性生物活性组分。这些类型的递送系统中的小颗粒尺寸（r < 100 nm）意味着它们对于某些应用具有许多潜在益处：增强的长期稳定性;高光学透明度;以及增加的生物利用度。目前，在科学文献中对术语“微乳液”和“纳米乳液”的使用存在相当大的混淆。然而，这些是明显不同类型的胶体分散体：微乳液是化学稳定的，而纳米乳液不是。因此，区分它们是很重要的，因为这会影响用于制造它们的方法，用于稳定它们的策略以及用于设计它们的功能属性的方法。本文综述了纳米乳液和微乳液在组成、结构、制备、性质和稳定性等方面的异同。它还试图强调为什么在这一领域有这么多的混乱，并澄清用于指这两种胶体分散体的术语。
Colloidal delivery systems based on microemulsions or nanoemulsions are increasingly being utilized in the food and pharmaceutical industries to encapsulate, protect, and deliver lipophilic bioactive components. The small size of the particles in these kinds of delivery systems (r < 100 nm) means that they have a number of potential benefits for certain applications: enhanced long-term stability; high optical clarity; and, increased bioavailability. Currently, there is considerable confusion about the use of the terms "microemulsions" and "nanoemulsions" in the scientific literature. However, these are distinctly different types of colloidal dispersions: a microemulsion is thermodynamically stable, whereas a nanoemulsion is not. It is therefore important to distinguish between them since this impacts the methods used to fabricate them, the strategies used to stabilize them, and the approaches used to design their functional attributes. This article reviews the differences and similarities between nanoemulsions and microemulsions in terms of their compositions, structure, fabrication, properties, and stability. It also attempts to highlight why there has been so much confusion in this area, and to clarify the terminology used to refer to these two kinds of colloidal dispersion.