Sickle cell "nondisease": a potentially serious public health problem.
Sickle cell "nondisease": a potentially serious public health problem.
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镰状细胞“非疾病”：一个潜在的严重公共卫生问题。
DOI：
10.1001/archpedi.1974.02110260060010
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发表时间：
1974
影响因子：
--
通讯作者：
M. L. Hampton
中科院分区：
文献类型：
--
作者：
M. L. Hampton
大规模的镰状细胞筛查计划已经仓促启动，几乎没有明显考虑到潜在的有害影响。为了评估这一程序的影响，在社区卫生中心对孩子进行筛查的父母在家中接受了采访，内容包括他们对镰状细胞特征作为健康因素的看法，对社会化的担忧，对携带者施加的“病态角色”，以及家庭和同龄人中社交功能受损的问题。结果表明，在接受测试的人中，对镰状细胞特征的意义存在很大的混淆。在黑人儿童中，镰状细胞“非疾病”可能会成为一个严重的国家公共卫生问题。证明这一程序利大于弊的责任应该落在那些主张继续开展大规模镰状细胞筛查计划的人身上。
Mass sickle cell screening programs have been hastily instituted with little apparent regard for potential harmful effects. In an attempt to gauge the impact of the procedure, parents whose children were screened at a neighborhood health center were interviewed in their homes about their perceptions of the sickle cell trait as a health factor, concerns about socialization, the imposition of the "sick role" on the carrier, and impaired social functioning within the family and peer groups. The results indicate that much confusion exists about the significance of sickle cell trait among those who were tested. Sickle cell "nondisease" might emerge as a serious national public health problem among black children. The burden of proof that the procedure does more good than harm should rest on those who advocate continuation of mass sickle cell screening programs.