Thymic involution with ageing: Obsolescence or good housekeeping?
Thymic involution with ageing: Obsolescence or good housekeeping?
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DOI：
10.1016/0167-5699(96)80543-3
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发表时间：
1996-06-01
期刊：
影响因子：
--
通讯作者：
Ritter, MA
中科院分区：
文献类型：
--
作者：
George, AJT;Ritter, MA
与免疫系统的其他器官相比，胸腺经历了过早的衰老，出生后不久就开始退化，并持续到一生。这是反映了修复的失败，还是适应过程的价值？在这里，安德鲁·乔治和玛丽·里特应用了成本效益分析，并得出结论，缩小这个器官的规模对我们的祖先来说是进化上的优势。
The thymus undergoes premature ageing in comparison with other organs of the immune system, with involution starting soon after birth and continuing throughout life. Does this reflect a failure of repair or is the process of adaptive value? Here, Andrew George and Mary Ritter apply a cost-benefit analysis, and conclude that the scaling down of this organ has been evolutionarily advantageous to our ancestors.