Catheter ablation of premature ventricular contraction-induced cardiomyopathy
Catheter ablation of premature ventricular contraction-induced cardiomyopathy
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DOI：
10.1038/ncpcardio1180
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发表时间：
2008-05-01
期刊：
影响因子：
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通讯作者：
Ward, David E.
中科院分区：
文献类型：
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作者：
Ezzat, Vivienne A.;Liew, Reginald;Ward, David E.
背景：一位44岁女性，有长期胸痛、心悸和呼吸困难的病史。心电图和24小时霍尔特监测显示多个室性早搏（PVC），超声心动图显示明显的左心室扩张和收缩功能障碍。经过进一步的研究，得出结论，这种心肌病是继发于观察到的多发性PVC，这些代表了一个潜在的治疗目标。使用多电极阵列导管进行倾斜测试和侵入性电生理测试。诊断PVC-心室异位病灶的电生理标测和冷冻消融治疗。
Background A 44-year-old female presented with a long history of chest pain, palpitations and increasing dyspnea. Electrocardiography and 24 h Holter monitoring revealed multiple premature ventricular complexes (PVCs), and echocardiography demonstrated significant left ventricular dilatation and systolic impairment. After further investigation it was concluded that this cardiomyopathy was secondary to the observed multiple PVCs and that these represented a potential target for treatment.Investigations Electrocardiography, echocardiography, cardiac MRI, 24 h Holter monitoring, coronary angiography, tilt testing and invasive electrophysiological testing using a multielectrode array catheter.Diagnosis PVC-induced dilated cardiomyopathy.Management Electrophysiological mapping and cryoablation of the focus of the ventricular ectopy.