Effects of various enzymes on the ability of hamster egg plasma membranes to fuse with spermatozoa

Effects of various enzymes on the ability of hamster egg plasma membranes to fuse with spermatozoa
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各种酶对仓鼠卵质膜与精子融合能力的影响

DOI:
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发表时间:
1978
期刊:
影响因子:
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通讯作者:
R. Yanagimachi
R. Yanagimachi
中科院分区:
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文献类型:
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作者:
Y. Hirao;R. Yanagimachi

文献摘要

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To investigate which component of the plasma membrane of the hamster egg plays the central role in the sperm–egg fusion, the egg membrane was treated with a variety of proteolytic, carbohydrate-hydrolyzing, lipid-hydrolyzing, and other enzymes. The only enzyme that markedly effected the ability of the egg membrane to fuse with spermatozoa was phospholipase C. The lipid moieties of the egg plasma membrane (and possibly of the sperm membrane) must be of primary importance in sperm–egg fusion at fertilization.