Ace-ylation in the hole.
Ace-ylation in the hole.
复制标题
孔中乙酰化。
DOI:
10.1038/s41589-022-01083-7
复制
发表时间:
2022
影响因子:
14.8
通讯作者:
FCravatt,Benjamin
中科院分区:
文献类型:
--
作者:
JNiphakis,Micah;FCravatt,Benjamin
Mutant-selective KRAS-targeting drugs hold great promise for the treatment of some of the most aggressive forms of cancer. Building on the breakthrough success of KRAS-G12C inhibitors, researchers have now found a way to target another mutant KRAS with serine-modifying covalent inhibitors.