A 3.1-5.2GHz, Energy-Efficient Single Antenna, Cancellation-Free, Bitwise Time-Division Duplex Transceiver for High Channel Count Optogenetic Neural Interface
A 3.1-5.2GHz, Energy-Efficient Single Antenna, Cancellation-Free, Bitwise Time-Division Duplex Transceiver for High Channel Count Optogenetic Neural Interface
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DOI：
10.1109/tbcas.2021.3139891
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发表时间：
2022-02-01
影响因子：
5.1
通讯作者：
Yoon, Euisik
中科院分区：
文献类型：
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作者：
Lin, Yu-Ju;Song, Hyunsoo;Yoon, Euisik
我们报告了一种高能效、无消除、逐位时分双工（B-TDD）收发器（TRX），用于高通道数神经接口的实时闭环控制。所提出的B-TDD架构由占空比超宽带（UWB）发射机（3.1-5 GHz）和开关U-NII频段（5.2 GHz）接收机组成。在单个天线中实现能量有效的双工，而不需要在传统的全双工、单天线收发器中优先使用的高功耗自干扰消除电路。为了抑制上行链路和下行链路之间的干扰并增强两者之间的隔离，我们在低噪声放大器中设计了一种快速切换方案，并在接收器中使用了内置赢家通吃投票的5倍过采样。该收发器采用65 nm CMOS RF工艺，在10 Mbps和200 Mbps时分别实现了0.32 nJ/B和9.7 pJ/B的低功耗。为了验证，B-TDD TRX已与mu LED光电电极和定制模拟前端集成电路集成在原型无线双向神经接口系统中。在转基因啮齿动物中成功地同时记录宽带神经信号和光刺激的体内操作被证明。
We report an energy-efficient, cancellation-free, bit-wise time-division duplex (B-TDD) transceiver (TRX) for real-time closed-loop control of high channel count neural interfaces. The proposed B-TDD architecture consists of a duty-cycled ultra-wide band (UWB) transmitter (3.1-5 GHz) and a switching U-NII band (5.2 GHz) receiver. An energy-efficient duplex is realized in a single antenna without power-hungry self-interference cancellation circuits which are prevalently used in the conventional full-duplex, single antenna transceivers. To suppress the interference between up- and down-links and enhance the isolation between the two, we devised a fast-switching scheme in a low noise amplifier and used 5x oversampling with a built-in winner-take-all voting in the receiver. The B-TDD transceiver was fabricated in 65 nm CMOS RF process, achieving low energy consumption of 0.32 nJ/b at 10 Mbps in the receiver and 9.7 pJ/b at 200 Mbps in the transmitter, respectively. For validation, the B-TDD TRX has been integrated with a mu LED optoelectrode and a custom analog frontend integrated circuit in a prototype wireless bidirectional neural interface system. Successful in-vivo operation for simultaneously recording broadband neural signals and optical stimulation was demonstrated in a transgenic rodent.