Dysglycemia and incident heart failure among blacks: The jackson heart study.
Dysglycemia and incident heart failure among blacks: The jackson heart study.
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DOI：
10.1016/j.ahj.2021.11.003
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发表时间：
2022-03
影响因子：
4.8
通讯作者：
Bertoni AG
中科院分区：
文献类型：
--
作者：
Echouffo-Tcheugui JB;Mwasongwe SE;Musani SK;Hall ME;Correa A;Hernandez AF;Golden SH;Mentz RJ;Bertoni AG
We aimed to investigate the associations of glycemic markers (hemoglobin A1C [HbA1C], fasting plasma glucose [FPG] and glycemic status [normoglycemia, prediabetes and diabetes]) with incident heart failure (HF) and its subtypes, among Blacks. We included 2,290 community-dwelling Blacks(64% women, mean age 58 years) without prevalent HF from the Jackson Heart Study who attended the second exam (2005–2008). The associations between glycemic markers and incident HF (and subtypes including HF with preserved ejection fraction [HFpEF] and reduced ejection fraction [HFrEF]) were evaluated using Cox proportional hazards regression models, adjusting for risk factors and coronary heart disease. There were 119 incident HF events (48 HFpEF, 58 HFrEF, and 13 unclassified HF events) over a median follow-up of 10.5 years. Higher levels of HbA1C (HR per SD increment, 1.30; 95% CI 1.12, 1.51) and FPG (HR per SD increment FPG: 1.32; 95% CI: 1.17, 1.48) were associated with a higher risk of incident HF. Compared to normal glycemia, diabetes status was associated with a higher risk of incident HF (HR: 1.24; 95%CI: 1.02, 2.05). HbA1C was significantly associated with higher risks of HFpEF (HR per SD increment: 1.41, 95% CI: 1.18, 1.69) and HFrEF (HR per SD increment: 1.32; 95% CI: 1.12, 1.56). FPG was significantly associated with higher risk of HFpEF (HR per SD increment: 1.35, 95% CI: 1.14, 1.62) but not HFrEF (HR per SD increment: 1.12; 95% CI: 0.53, 2.35). Among community-dwelling Blacks, higher levels of glycemic markers were associated with higher risk of HF subtypes. NCT00005485) of the Jackson Heart Study.
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影响因子：
24
作者：
McGuire DK;Shih WJ;Cosentino F;Charbonnel B;Cherney DZI;Dagogo-Jack S;Pratley R;Greenberg M;Wang S;Huyck S;Gantz I;Terra SG;Masiukiewicz U;Cannon CP
通讯作者：
Cannon CP
影响因子：
120.7
作者：
Menke, Andy;Casagrande, Sarah;Cowie, Catherine C.
通讯作者：
Cowie, Catherine C.
影响因子：
8.2
作者：
Pazin-Filho, A.;Kottgen, A.;Bertoni, A. G.;Russell, S. D.;Selvin, E.;Rosamond, W. D.;Coresh, J.
通讯作者：
Coresh, J.
影响因子：
4.8
作者：
Echouffo-Tcheugui, Justin B.;Xu, Haolin;Fonarow, Gregg C.
通讯作者：
Fonarow, Gregg C.
影响因子：
5.8
作者：
Herman, William H.;Cohen, Robert M.
通讯作者：
Cohen, Robert M.