Ni(II)-catalyzed conia-ene reaction of 1,3-dicarbonyl compounds with alkynes
Ni(II)-catalyzed conia-ene reaction of 1,3-dicarbonyl compounds with alkynes
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DOI：
10.1021/ol050532q
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发表时间：
2005-05-26
期刊：
影响因子：
5.2
通讯作者：
Yang, D
中科院分区：
文献类型：
--
作者：
Gao, Q;Zheng, BF;Yang, D
我们发现了镍(II)催化的1，3-二羰基化合物与炔烃的Conia-ene反应。在Ni(Acac)(2)和Yb(OTf)(3)存在下，各种乙酰基1，3-二羰基化合物发生Conia-ene反应，得到单环和双环的烯烃环戊烷。提出了一种涉及烯醇-炔-镍络合物形成的机理，并得到了氚标记实验的支持。
We have discovered a Ni(II)-catalyzed Conia-ene reaction of 1,3-dicarbonyl compounds with alkynes. In the presence of Ni(acac)(2) and Yb(OTf)(3), various acetylenic 1,3-dicarbonyl compounds underwent Conia-ene reaction to give mono- and bicyclic olefinic cyclopentanes. A mechanism involving the enol-yne-Ni complex formation is proposed and supported by deuterium-labeling experiments.