Yeast cytochrome c oxidase: a model system to study mitochondrial forms of the haem-copper oxidase superfamily.
Yeast cytochrome c oxidase: a model system to study mitochondrial forms of the haem-copper oxidase superfamily.
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DOI：
10.1016/j.bbabio.2011.08.011
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发表时间：
2012-04
期刊：
影响因子：
--
通讯作者：
Rich PR
中科院分区：
文献类型：
--
作者：
Maréchal A;Meunier B;Lee D;Orengo C;Rich PR
综述了酵母线粒体细胞色素c氧化酶的已知亚基。所有11个亚基的结构进行了探索，通过建立同源模型的基础上公布的同源牛亚基的结构和相似性和差异突出，特别是核心功能亚基I。酵母遗传技术，使引入突变到三个核心的编码亚基进行审查。这篇文章是题为：呼吸氧化酶的特刊的一部分。
The known subunits of yeast mitochondrial cytochrome c oxidase are reviewed. The structures of all eleven of its subunits are explored by building homology models based on the published structures of the homologous bovine subunits and similarities and differences are highlighted, particularly of the core functional subunit I. Yeast genetic techniques to enable introduction of mutations into the three core mitochondrially-encoded subunits are reviewed. This article is part of a Special Issue entitled: Respiratory Oxidases.