The PROSITE database, its status in 2002

The PROSITE database, its status in 2002
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DOI:
10.1093/nar/30.1.235
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发表时间:
2002-01-01
影响因子:
14.9
通讯作者:
Bairoch, A
Bairoch, A
中科院分区:
生物学2区
文献类型:
--
作者:
Falquet, L;Pagni, M;Bairoch, A

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ProSITE [Bairoch和布赫(1994)Nucleic Acids Res.,22,3583-3589; Hofmann等人(1999)Nucleic Acids Res.,27,215-219]是鉴定从基因组或cDNA序列翻译的未表征蛋白质的功能的方法。PROSITE数据库(http://www.expasy.org/prosite/)由生物学上重要的模式和特征组成,其设计方式使得使用适当的计算工具,它可以快速可靠地帮助确定新序列属于哪个已知蛋白质家族(如果有的话),或者它包含哪个已知结构域。
PROSITE [Bairoch and Bucher (1994) Nucleic Acids Res., 22, 3583-3589; Hofmann et al. (1999) Nucleic Acids Res., 27, 215-219] is a method of identifying the functions of uncharacterized proteins translated from genomic or cDNA sequences. The PROSITE database (http://www.expasy.org/prosite/) consists of biologically significant patterns and profiles designed in such a way that with appropriate computational tools it can rapidly and reliably help to determine to which known family of proteins (if any) a new sequence belongs, or which known domain(s) it contains.