Factors Associated With Anastomotic Recurrence After Total Mesorectal Excision in Rectal Cancer Patients
Factors Associated With Anastomotic Recurrence After Total Mesorectal Excision in Rectal Cancer Patients
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DOI：
10.1002/jso.21166
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发表时间：
2009-01-01
影响因子：
2.5
通讯作者：
Cho, Chang-Hwan
中科院分区：
文献类型：
--
作者：
Kim, Young-Wan;Kim, Nam-Kyu;Cho, Chang-Hwan
Background: In patients undergoing total mesorectal excision (TME), the clinical variables most relevant to anastomotic recurrence have not been identified. We evaluated factors associated with anastomotic recurrence in patients undergoing TME and the impact of a reduced distal margin on anastomotic recurrence.Methods: Thirty-eight patients with anastomotic recurrence were compared with 876 patients who received curative rectal cancer surgery. Patients were compared according to: (1) the presence of anastomotic recurrence (recurrence vs. recurrence-free), (2) distal margin length (10 mm) and (3) additional treatment (none, adjuvant, or neoadjuvant). The risk factors for anastomotic recurrence were analyzed.Results: In the recurrence group, an advanced T stage (T3 and T4) (P = 0.01) microscopic distal margin involvement (P = 0.002) and an elevated CEA level (>5 ng/ml) (P = 0.04) were more commonly found. The incidence of anastomotic recurrence was not higher in the distal margin
