TETRACYCLINE-LABELED HUMAN-BONE FROM ANCIENT SUDANESE NUBIA (AD 350)
TETRACYCLINE-LABELED HUMAN-BONE FROM ANCIENT SUDANESE NUBIA (AD 350)
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DOI：
10.1126/science.7001623
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发表时间：
1980-01-01
期刊：
影响因子：
56.9
通讯作者：
VILLANUEVA, AR
中科院分区：
文献类型：
--
作者：
BASSETT, EJ;KEITH, MS;VILLANUEVA, AR
从X群墓地(公元350-550)发现的努比亚骨骼显示出与现代四环素标记骨骼相同的荧光模式。当它在490埃的紫外光下观察时，在曝光时正在活跃的矿化的表面上，可以看到荧光体作为特征的黄绿色荧光。储存谷物的污染为四环素产生链霉菌的培养提供了适宜的环境。考古人群中接触抗生素的证据与研究R因子的演变以及解释人群中的健康和疾病有关。
Nubian bone recovered from an X-group cemetery (A.D. 350 to 550) exhibits a pattern of fluorescence identical to that of modern tetracycline-labeled bone. When it is viewed under UV light at 490 angstroms, fluorophors are visible as a characteristic yellow-green fluorescence on surfaces that were actively mineralizing at the time of exposure. Contamination of stored grains provided the proper environment for cultivation of tetracycline-producing streptomycetes. Evidence for exposure to antibiotics in an archeological population is relevant to studies of the evolution of R factors and to the interpretation of health and disease within the population.