The hyaluronan receptor, CD44
The hyaluronan receptor, CD44
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DOI：
10.1016/s1357-2725(01)00166-2
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发表时间：
2002-07-01
影响因子：
4
通讯作者：
Yarwood, H
中科院分区：
文献类型：
--
作者：
Isacke, CM;Yarwood, H
CD44是广泛表达的细胞表面透明质酸受体，其在介导细胞迁移中起关键作用。最近的一些论文证明了CD44和基质金属蛋白酶（MMPs）之间的相互作用，这些事件的分子机制的重要见解。这对于理解CD44的错误调节如何有助于疾病病理学具有重要意义。(C)2002年由Elsevier Science Ltd.出版
CD44 is a widely expressed cell surface hyaluronan receptor which plays a key role in mediating cell migration. A number of recent papers demonstrating an interplay between CD44 and matrix metalloproteinases (MMPs) have shed important insights into the molecular mechanisms underlying these events. This has important implication for understanding how mis-regulation of CD44 can contribute to disease pathologies. (C) 2002 Published by Elsevier Science Ltd.