LH/hCG action and development of ovarian cancer - A short review on biological and clinical/epidemiological aspects
LH/hCG action and development of ovarian cancer - A short review on biological and clinical/epidemiological aspects
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DOI：
10.1016/j.mce.2006.11.014
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发表时间：
2007-04-15
影响因子：
4.1
通讯作者：
Fujii, Shingo
中科院分区：
文献类型：
--
作者：
Mandai, Masaki;Konishi, Ikuo;Fujii, Shingo
自从1992年一份流行病学报告支持这种可能性以来，不孕不育治疗，特别是促性腺激素诱导排卵治疗与卵巢癌的发展之间的联系一直是一个有争议的问题。一些临床/流行病学和生物学研究，包括我们进行的几项研究，揭示了有关这一问题的各种事实。这一简短审查的目的是总结过去10年的调查结果，并讨论关于这一问题的辩论所涉问题。(C)2007爱思唯尔爱尔兰有限公司。保留所有权利。
A link between infertility therapy, especially ovulation induction therapy using gonadotropins, and the development of ovarian cancer has long been an issue of debate since an epidemiological report supporting the possibility appeared in 1992. A number of clinical/epidemiological and biological studies, including a few that we conducted, have revealed various facts regarding this issue. The aim of this short review was to summarize the last 10 years findings and to address the implications of the debates on this issue. (c) 2007 Elsevier Ireland Ltd. All rights reserved.