A repeated measures concordance correlation coefficient

A repeated measures concordance correlation coefficient
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DOI:
10.1002/sim.2778
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发表时间:
2007-07-20
影响因子:
2
通讯作者:
Carrasco, Josep L.
Carrasco, Josep L.
中科院分区:
医学3区
文献类型:
--
作者:
King, Tonya S.;Chinchilli, Vernon M.;Carrasco, Josep L.

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当以连续尺度测量数据时,一致性相关系数通常用于评估两个评估者或两种测量响应的方法之间的一致性。然而,可能会出现对每个评估者或方法进行重复测量的情况,例如临床试验或生物测定数据中子样本的纵向研究。本文提出了一个系数,用于测量两个评估者之间的一致性或在存在重复测量的情况下测量响应的两种方法。我们通过示例来说明该方法,比较了 (1) 哮喘临床试验中用于测量皮质醇的 1 小时与 2 小时抽血,以及 (2) 通过皮褶卡尺和双能 X 射线吸收测定法两次测量身体脂肪百分比。版权所有 (C) 2007 John Wiley & Sons, Ltd.
The concordance correlation coefficient is commonly used to assess agreement between two raters or two methods of measuring a response when the data are measured on a continuous scale. However, the situation may arise in which repeated measurements are taken for each rater or method, e.g. longitudinal studies in clinical trials or bioassay data with subsamples. This paper proposes a coefficient for measuring agreement between two raters or two methods of measuring a response in the presence of repeated measurements. We illustrate the methodology with examples comparing (1) 1-hr versus 2-hr blood draws for measuring cortisol in an asthma clinical trial and (2) two measurements of percentage body fat, from skinfold calipers and dual energy X-ray absorptiometry. Copyright (C) 2007 John Wiley & Sons, Ltd.