Balancing act during development: lessons from a SUMO-less SF-1.
Balancing act during development: lessons from a SUMO-less SF-1.
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开发过程中的平衡行为:无 SUMO SF-1 的经验教训。
DOI:
10.1016/j.devcel.2011.07.015
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发表时间:
2011
影响因子:
11.8
通讯作者:
Yeh,EdwardTH
中科院分区:
文献类型:
--
作者:
Lin,Feng-Ming;Yeh,EdwardTH
When a transcription factor is modified by small ubiquitin-like modifier (SUMO), this usually represses its transcriptional activity. In this issue ofDevelopmental Cell, Lee et al. (2011) use a knockin mouse model to show that SUMO-less SF-1 binds and activates inappropriate targets, causing changes in cell fates and endocrine abnormalities.
影响因子:
4
作者:
Wang, Yonggang;Dasso, Mary
通讯作者:
Dasso, Mary
影响因子:
16
作者:
Kang X;Qi Y;Zuo Y;Wang Q;Zou Y;Schwartz RJ;Cheng J;Yeh ET
通讯作者:
Yeh ET