Mortality from infectious pneumonia in metal workers: a comparison with deaths from asthma in occupations exposed to respiratory sensitisers
Mortality from infectious pneumonia in metal workers: a comparison with deaths from asthma in occupations exposed to respiratory sensitisers
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DOI：
10.1136/thx.2009.114280
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发表时间：
2009-11-01
期刊：
影响因子：
10
通讯作者：
Coggon, D.
中科院分区：
文献类型：
--
作者：
Palmer, K. T.;Cullinan, P.;Coggon, D.
背景：英格兰和威尔士的国家死亡率分析一再显示焊工肺炎死亡率过高。1979- 1990年期间，死亡人数的增加主要是由于支气管肺炎以外的大叶性肺炎和肺炎造成的，这些死亡仅限于工作年龄的男子，而且在接触金属烟雾的其他职业中也很明显。1991-2000年的调查结果进行了评估，并与职业暴露于已知的呼吸道sensitisers.Methods哮喘的死亡率模式进行了比较：国家统计局提供的数据，在1991-2000年期间，年龄在16-74岁的男性在英格兰和威尔士的根本原因，包括年龄和最后举行的职业。收集了暴露于金属烟雾的职业的肺炎数据和监测计划中通常报告的职业哮喘风险职业的哮喘数据。预计死亡人数的估算方法是，将人口中按年龄分列的死因死亡比例与每一职业类别按年龄分列的死亡总数相比较。观察到的和预期的数字进行了比较，为每个causeofdeath.Results：在男性的工作年龄在职业接触金属烟雾有过多的死亡率肺炎球菌和大叶性肺炎（54例死亡与27.3预期）和肺炎以外的支气管肺炎（71比52.4），但没有多余的这些原因在老年人或支气管肺炎在任何年龄。金属烟雾暴露的归因死亡率为45.3多死亡相比，估计62.6例死亡，从职业asthene.Conclusion：金属烟雾暴露是职业性死亡的一个重要原因。这种危险值得比现在更多的关注。
Background: National analyses of mortality in England and Wales have repeatedly shown excess deaths from pneumonia in welders. During 1979-90 the excess was attributable largely to deaths from lobar pneumonia and pneumonias other than bronchopneumonia, limited to men of working age and apparent in other occupations with exposure to metal fumes. The findings for 1991-2000 were assessed and compared with the mortality pattern from asthma in occupations exposed to known respiratory sensitisers.Methods: The Office of National Statistics supplied data on deaths by underlying cause among men aged 16-74 years in England and Wales during 1991-2000, including age and last held occupation. Data were abstracted on pneumonia for occupations with exposure to metal fumes and on asthma for occupations commonly reported to surveillance schemes as at risk of occupational asthma. The expected numbers of deaths were estimated by applying age-specific proportions of deaths by cause in the population to the total deaths by age in each occupational group. Observed and expected numbers were compared for each cause of death.Results: Among men of working age in occupations with exposure to metal fumes there was excess mortality from pneumococcal and lobar pneumonia (54 deaths vs 27.3 expected) and from pneumonias other than bronchopneumonia (71 vs 52.4), but no excess from these causes at older ages or from bronchopneumonia at any age. The attributable mortality from metal fume exposure was 45.3 excess deaths compared with an estimated 62.6 deaths from occupational asthma.Conclusion: Exposure to metal fumes is a material cause of occupational mortality. The hazard deserves far more attention than it presently receives.