Assessment of adiposity in an Indian population: familial correlations.
Assessment of adiposity in an Indian population: familial correlations.
复制标题
印度人群肥胖的评估：家族相关性。
DOI：
10.1002/gepi.1370100206
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发表时间：
1993
影响因子：
2.1
通讯作者：
Rao,DC
中科院分区：
文献类型：
--
作者：
Nirmala,A;Mitchell,LE;Rice,T;Reddy,PC;Rao,DC
使用居住在印度安得拉邦奇图尔区的473个核心家庭的数据，对五种肥胖指标的家庭相关性进行了评估。通过测量躯干与四肢皮下脂肪的比值、肩胛下皮褶与髂上皮褶总和的比值，以及体重指数、6个皮褶总和和3个躯干皮褶总和3个综合肥胖度指标，对肥胖模式进行分析。在调整了(1)性别内年龄和(2)当前能量摄入和消耗水平以及性别内年龄的影响后，获得了每种表型的家庭相关性的最大似然估计。在两种调整方案下，对每种表型的性别特异性和代际差异的相关性的假设进行了评估。对数据进行的具体调整显著影响了三种普遍肥胖衡量标准的家族相关性的强度和模式。相反，在两种调整方案下，脂肪模式表型的家族相关性非常相似。我们的结果与以前发表的数据的比较表明，这些肥胖症指标的子集的家族相关性可能在不同人群中是不同的。©1993 Wiley-Liss。Inc.
Familial correlations for five measures of adiposity were assessed using data from 473 nuclear families residing in the Chittoor district of Andhra Pradesh, India. Fat patterning, measured as the ratio of trunk to extremity subcutaneous fat, and the ratio of the subscapular to the sum of the subscapular and suprailiac skinfolds, and three measures of generalized fatness: body mass index, the sum of six skinfolds and the sum of three trunk skinfolds were analyzed. Maximum likelihood estimates of the familial correlations were obtained for each phenotype, after adjusting for the effects of (1) age within sex, and (2) current levels of energy intake and expenditure, and age within sex. Hypotheses regarding sex‐specific, and generational differences in these correlations were assessed for each phenotype, under both adjustment schemes. The strength and pattern of the familial correlations for the three measures of generalized fatness were markedly influenced by the specific adjustments applied to the data. In contrast, the familial correlations for the fat patterning phenotypes were quite similar under the two adjustment schemes. Comparison of our results with previously published data indicates that the familial correlations for a subset of these adiposity measures may be heterogeneous across populations. © 1993 Wiley‐Liss. Inc.