A peer navigation intervention to prevent HIV among mixed immigrant status Latinx GBMSM and transgender women in the United States: outcomes, perspectives and implications for PrEP uptake
A peer navigation intervention to prevent HIV among mixed immigrant status Latinx GBMSM and transgender women in the United States: outcomes, perspectives and implications for PrEP uptake
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DOI：
10.1093/her/cyaa010
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发表时间：
2020-06-01
影响因子：
2.4
通讯作者：
Reboussin, Beth A.
中科院分区：
文献类型：
--
作者：
Rhodes, Scott D.;Alonzo, Jorge;Reboussin, Beth A.
美国的拉丁裔人口受到艾滋病毒的影响不成比例。我们以社区为基础的参与性研究伙伴关系开发、实施并评估了一项西班牙语同伴导航干预措施，旨在增加西班牙裔拉丁裔移民同性恋、双性恋和其他男男性行为者（GBMSM）以及变性女性（TW）的社会网络中艾滋病毒检测和安全套的使用。我们随机选取21个拉丁裔GBMSM和TW的社交网络，年龄在18-55岁之间，进行干预，称为HOLA，或等候名单对照组。社会网络参与者（n=166）在基线和12个月的随访（基线后24个月）完成结构化评估。随访保留率为95%。与参与者样本进行的个人深度访谈记录了他们与干预相关的经验、需求和优先事项，为未来的研究提供信息。在随访中，HOLA参与者报告HIV检测增加（校正优势比=8.3;95% CI=3.0-23.0; P < 0.0001）。所有研究参与者都报告避孕套的使用增加了；HOLA和候补名单对照组之间没有显著差异。深入访谈确定了关键的干预要素和影响以及社区需求和优先事项。HOLA干预措施对于增加拉丁裔gbsm和TW中的艾滋病毒检测是有效的，这是艾滋病毒预防和护理持续的第一步，并且可能适用于促进暴露前预防的吸收。
The Latinx population in the United States is disproportionately affected by HIV. Our community-based participatory research partnership developed, implemented and evaluated a Spanish-language peer navigation intervention designed to increase HIV testing and condom use among social networks of immigrant Spanish-speaking Latinx gay, bisexual and other men who have sex with men (GBMSM) and transgender women (TW). We randomized 21 social networks of Latinx GBMSM and TW, ages 18-55years, to the intervention, known as HOLA, or a waitlist control group. Social network participants (n=166) completed structured assessments at baseline and 12-month follow-up (24months after baseline). Follow-up retention was 95%. Individual in-depth interviews with a sample of participants documented their intervention-related experiences, needs, and priorities to inform future research. At follow-up, HOLA participants reported increased HIV testing (adjusted odds ratio=8.3; 95% CI=3.0-23.0; P < 0.0001). All study participants reported increased condom use; there was no significant difference between HOLA and waitlist control participants. In-depth interviews identified critical intervention elements and impacts and community needs and priorities. The HOLA intervention is effective for increasing HIV testing among Latinx GBMSM and TW, an initial step within the HIV prevention and care continua, and may be adaptable to promote pre-exposure prophylaxis uptake.