Julian Hart Lewis, F.R.S. (1946-2014).
Julian Hart Lewis, F.R.S. (1946-2014).
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朱利安·哈特·刘易斯，F.R.S.
DOI：
10.1016/j.devcel.2014.05.019
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发表时间：
2014
影响因子：
11.8
通讯作者：
Whitfield TT
中科院分区：
文献类型：
--
作者：
Whitfield TT
朱利安刘易斯，发展生物学家，理论家，作家，通晓多种语言，朋友，和许多人的灵感，去世了67岁。朱利安以其温和的个性和罕见的物理学、数学和生物学专业知识的结合而闻名，他被广泛认为是一位才华横溢的原创科学家，为发育生物学领域做出了许多重要贡献。特别是，正是通过他对Notch信号通路的分析-在整个组织范围内-朱利安取得了他的成绩，使用仔细的理论推理和优雅的实验设计将这一研究领域推向新的方向。朱利安开始了他的职业生涯在物理科学，阅读物理在贝利奥尔学院作为一个本科生，并留在牛津大学攻读博士学位。在莫斯科物理问题研究所做了一年博士后后，他开始在伦敦米德尔塞克斯医院医学院的刘易斯·沃尔珀特实验室研究鸡胚。他在伦敦国王学院解剖学系担任讲师8年，然后于1986年加入牛津帝国癌症研究基金会发育生物学单位担任组长。十年后，实验室搬到了位于伦敦林肯酒店的伦敦研究所，朱利安在那里工作直到2012年退休。他继续以名誉退休的身份进行研究和写作，他的最新论文发表于2014年4月。那些有幸通过朱利安实验室的人回忆起一位支持和令人愉快的古怪导师，他是一座信息和专业知识的宝库。朱利安对一切都很感兴趣，阅读范围非常广泛。谈话的范围从家庭到法语语法。他的物理学背景意味着他理解复合或共聚焦显微镜的光学原理，他喜欢帮助设置一切，以最好地利用实验室中的任何设备。但他不仅关心科学贡献：朱利安总是有兴趣听到实验室成员的家庭是如何做的，没有什么比拥抱和欣赏一个新的婴儿更喜欢的了。
Julian Lewis, developmental biologist, theoretician, writer, polyglot, friend, and inspiration to many, has died aged 67. Known for his gentle personality and rare combination of expertise in physics, mathematics, and biology, Julian was widely acknowledged as a brilliant and original scientist who made many important contributions to the field of developmental biology. In particular, it was through his analysis of the Notch signaling pathway—in a whole range of tissues—that Julian made his mark, driving this research field in new directions using both careful theoretical reasoning and elegant experimental design. Julian began his career in the physical sciences, reading physics at Balliol College as an undergraduate and staying on in Oxford to study for a DPhil. After a postdoctoral year at the Institute for Physical Problems in Moscow, he began work on the chick embryo in the laboratory of Lewis Wolpert at the Middlesex Hospital Medical School, London. He worked as a lecturer in the Department of Anatomy at King’s College London for 8 years before he joined the Imperial Cancer Research Fund’s Developmental Biology Unit in Oxford as a group leader in 1986. Ten years later, the lab moved to the London Research Institute at Lincoln’s Inn Fields in London, whereJulian worked until his retirement in 2012. He continued with research and writing in an emeritus capacity, with his latest paper appearing in April 2014. Those who were fortunate enough to have passed through Julian’s lab recall a supportive and delightfully quirky mentor who was a mine of information and expertise. Julian was interested in everything and read extremely widely. Conversations ranged from the family to French grammar. His physics background meant that he understood the optics of a compound or confocal microscope inside out, and he loved to help in setting everything up to get the very best out of any equipment in the lab. But he wasn’t only concerned with scientific contributions: Julian was always interested to hear how the families of lab members were doing and loved nothing better than to hold and admire a new baby.