Walking compared with vigorous exercise for the prevention of cardiovascular events in women
Walking compared with vigorous exercise for the prevention of cardiovascular events in women
复制标题
DOI：
10.1056/nejmoa021067
复制
发表时间：
2002-09-05
影响因子：
158.5
通讯作者：
Siscovick, DS
中科院分区：
文献类型：
--
作者：
Manson, JE;Greenland, P;Siscovick, DS
背景：与剧烈运动相比，步行在预防心血管疾病中的作用仍存在争议。数据的妇女是少数民族或ethnic groups的成员是特别sparse.Methods：我们前瞻性地研究了总的身体活动评分，步行，剧烈运动，坐着的时间作为冠状动脉事件和总的心血管事件的发病率的预测因素73,743绝经后妇女50至79岁的妇女的健康倡议观察性研究。基线时，参与者没有被诊断出心血管疾病和癌症，所有参与者都完成了关于身体活动的详细问卷。我们记录了345例新诊断的冠心病和1551总心血管事件。结果：增加体力活动评分有很强的，分级，与冠状动脉事件和总心血管事件的风险呈负相关。在白色妇女和黑人妇女中也有类似的发现。以代谢当量（MET评分）衡量的能量消耗增加五分之一的女性，经年龄调整的冠状动脉事件相对风险分别为1.00、0.73、0.69、0.68和0.47（趋势P，
Background: The role of walking, as compared with vigorous exercise, in the prevention of cardiovascular disease remains controversial. Data for women who are members of minority racial or ethnic groups are particularly sparse.Methods: We prospectively examined the total physical-activity score, walking, vigorous exercise, and hours spent sitting as predictors of the incidence of coronary events and total cardiovascular events among 73,743 postmenopausal women 50 to 79 years of age in the Women's Health Initiative Observational Study. At base line, participants were free of diagnosed cardiovascular disease and cancer, and all participants completed detailed questionnaires about physical activity. We documented 345 newly diagnosed cases of coronary heart disease and 1551 total cardiovascular events.Results: An increasing physical-activity score had a strong, graded, inverse association with the risk of both coronary events and total cardiovascular events. There were similar findings among white women and black women. Women in increasing quintiles of energy expenditure measured in metabolic equivalents (the MET score) had age-adjusted relative risks of coronary events of 1.00, 0.73, 0.69, 0.68, and 0.47, respectively (P for trend,