Spinal cord blood flow in response to focal compression.
Spinal cord blood flow in response to focal compression.
复制标题
脊髓血流对局灶性压迫的反应。
DOI：
10.1097/00002517-199009000-00003
复制
发表时间：
1990
期刊：
影响因子：
--
通讯作者：
A. E. Jensen
中科院分区：
文献类型：
--
作者：
P. Hitchon;G. Dyste;R. Osenbach;M. M. Todd;T. Yamada;A. E. Jensen
麻醉后的绵羊在T13时通过可膨胀的硬膜外球囊压迫脊髓至200 mm Hg。8只动物受压20 min， 10只动物受压40 min， 12只动物受压80 min。脊髓血流量（SCBF）和脊髓诱发电位（sep）从L7到C7，反之亦然，在压缩前，压缩中，压缩1/2，压缩1/2，压缩2 /2和压缩后3 /2小时。在20分钟和40分钟组中，创伤区表现出充血反应。在80分钟组，SCBF恢复到基线。在压迫下，所有动物的sep都消失了，并且在损伤后3 1/2小时后未能恢复，无论压迫时间如何。这些结果表明，脊髓受压损伤后的再灌注并不伴随着sep的恢复。
Anesthetized sheep were subjected to spinal cord compression to 200 mm Hg at T13 by means of a distensible epidural balloon. Eight animals were subjected to compression for 20 min, 10 animals for 40 min, and 12 animals for 80 min. Spinal cord blood flow (SCBF) and spinal evoked potentials (SEPs) from L7 to C7 and vice versa were measured prior to, during, and 1/2, 1 1/2, 2 1/2, and 3 1/2 h following compression. The traumatized zone manifested a hyperemic response subsequent to balloon withdrawal in the 20-min and 40-min groups. In the 80-min group, SCBF returned to baseline. With compression, SEPs were obliterated in all animals and failed to recover after 3 1/2 h following injury, irrespective of the duration of compression. These results show that reperfusion of the cord following a compressive insult is not accompanied with recovery of SEPs.