Distribution of Cryptosporidium species in sheep in the UK
Distribution of Cryptosporidium species in sheep in the UK
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DOI：
10.1016/j.vetpar.2008.03.021
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发表时间：
2008-07-04
影响因子：
2.6
通讯作者：
Chalmers, Rachel M.
中科院分区：
文献类型：
--
作者：
Mueller-Doblies, Doris;Giles, Michaela;Chalmers, Rachel M.
关于绵羊隐孢子虫种属和基因型分布的研究很少，而且由于人类主要病原体之一微小隐孢子虫（Cryptosporidiumparvum）并不总是被发现，因此隐孢子虫病的潜在人畜共患性一直受到质疑。为了调查英国的情况，我们进行了三项研究：对被确定为暴露于人类隐孢子虫病病例的羊群进行反应性取样;以及在一个开放式农场对羔羊进行筛查。C.在新生羔羊隐孢子虫病中发现的唯一物种是细小孢子虫，并且在对人类隐孢子虫病病例反应性取样的羊群中占优势。C.在后一项研究中也发现了bovis，但频率低于C.小的C.在筛选计划中，在孤儿羔羊中发现了牛和鹿的基因型。这些研究结果表明，C.小隐孢子虫在新生羔羊腹泻中很重要，在英国的羊群中广泛存在，但也存在其他隐孢子虫属物种和基因型。绵羊，特别是小羊羔，仍然被认为是C。人类的细小病毒感染。皇冠版权所有（C）2008年出版的爱思唯尔B. V.保留所有权利。
There have been few studies of the distribution of Cryptosporidium species and genotypes in sheep, and the anthropozoonotic potential has been questioned since one of the major human pathogens, Cryptosporidium parvum, is not always found. To investigate the situation in the UK we undertook three studies: a reactive sampling programme of flocks identified as exposures for human cases of cryptosporidiosis; investigation of neonatal cryptosporidiosis in lambs; and a screening programme of lambs at an open farm. C. parvum was the only species found in neonatal lambs with cryptosporidiosis, and predominated in flocks sampled reactively to a human case of cryptosporidiosis. C. bovis was also found in the latter study but at a lower frequency than C. parvum. C. bovis and the cervine genotype were found in the orphan lambs under the screening programme. The results of these studies show that C. parvum is important in neonatal lamb diarrhoea and is widespread in sheep flocks in the UK, but that other Cryptosporidium species and genotypes are also present. Sheep, and young lambs in particular, must still be considered as a source of C. parvum infection for humans. Crown Copyright (C) 2008 Published by Elsevier B.V. All rights reserved.