How lymphocytes add up.

How lymphocytes add up.
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淋巴细胞如何累加。

DOI:
10.1038/ni.3636
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发表时间:
2016
期刊:
影响因子:
30.5
通讯作者:
Asquith B
Asquith B
中科院分区:
医学1区
文献类型:
--
作者:
Asquith B

文献摘要

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在获得性免疫中,一个令人惊讶的信号整合和程序性增殖的分子机制已经被确定:细胞周期调节因子Myc使淋巴细胞能够增加其接收的信号强度,并相应地调整其反应时间。
A surprising molecular mechanism underlying signal integration and programmed proliferation in adaptive immunity has been identified: the cell-cycle regulator Myc enables a lymphocyte to add up the strength of signals it receives and time its response accordingly.