Motives, diversion and routes of administration associated with nonmedical use of prescription opioids
Motives, diversion and routes of administration associated with nonmedical use of prescription opioids
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DOI：
10.1016/j.addbeh.2006.05.022
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发表时间：
2007-03-01
影响因子：
4.4
通讯作者：
Teter, Christian J.
中科院分区：
文献类型：
--
作者：
McCabe, Sean Esteban;Cranford, James A.;Teter, Christian J.
目的：本研究的主要目的是评估与处方阿片类药物的非医疗使用相关的动机、转移来源和给药途径，以及检查与处方阿片类药物的非医疗使用相关的物质使用相关问题。一种自我管理的，2005年，在美国中西部一所大型公立四年制大学进行了一项横断面网络调查，采用基于概率的抽样方法。最后的样本包括4580名全日制本科生。结果：处方阿片类药物的非医疗用途相关的三个最常见的动机是减轻疼痛，获得高，实验。处方类阿片的主要来源是朋友和父母，尽管在主要来源的报告中存在性别差异。每10名非医疗使用者中就有超过1人报告了鼻内给药。多变量分析表明，非医疗用户的处方阿片类药物谁使用的动机以外，以减轻疼痛，获得这些药物从非父母的来源，或使用这些药物通过非口服途径的管理显着更有可能遇到物质使用相关的problems.Conclusions：这些结果表明，非医疗使用处方阿片类药物是一个相当大的问题，为特定的亚组的大学生。虽然需要更多的研究，但本研究为处方阿片类药物滥用的政策和研究提供了重要的新方向。(c)2006爱思唯尔有限公司保留所有权利。
Objectives: The main objectives of this study were to assess the motives, diversion sources and routes of administration associated with the nonmedical use of prescription opioids as well as to examine substance use related problems associated with the nonmedical use of prescription opioids.Method: A self-administered, cross-sectional Web survey was conducted in 2005 at a large public Midwestern 4-year university in the U.S. using a probability-based sampling approach. The final sample included 4580 full-time undergraduate students.Results: The three most common motives associated with the nonmedical use of prescription opioids were to relieve pain, get high, and experiment. The leading sources of prescription opioids were friends and parents although there were gender differences in reports of primary sources. More than I in every 10 nonmedical users reported intranasal administration. Multivariate analyses indicated nonmedical users of prescription opioids who used for motives other than to relieve pain, obtained these drugs from non-parental sources, or used these drugs via non-oral routes of administration were significantly more likely to experience substance use related problems.Conclusions: These results indicate that nonmedical use of prescription opioids represents a considerable problem for particular subgroups of college students. While additional research is needed, the present study offers important new directions for policy and research regarding prescription opioid misuse. (c) 2006 Elsevier Ltd. All rights reserved.