COMPARATIVE RESPIRATORY EFFECTS OF OZONE AND AMBIENT OXIDANT POLLUTION EXPOSURE DURING HEAVY EXERCISE
COMPARATIVE RESPIRATORY EFFECTS OF OZONE AND AMBIENT OXIDANT POLLUTION EXPOSURE DURING HEAVY EXERCISE
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DOI：
10.1080/00022470.1984.10465814
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发表时间：
1984-01-01
期刊：
影响因子：
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通讯作者：
HACKNEY, JD
中科院分区：
文献类型：
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作者：
AVOL, EL;LINN, WS;HACKNEY, JD
在洛杉矶郊区[美国加利福尼亚州]，骑自行车的志愿者 (50) 暴露于含有 O3 的受控浓度为 0、0.08、0.16、0.24 和 0.32 ppm 的净化空气中，以及氧化剂污染的环境空气中（平均 O3 浓度为 0.15 ppm，平均总颗粒物浓度为 295 μg/m3）。暴露（按随机顺序，间隔 14 天）涉及 1 小时的剧烈连续运动（平均每分钟运动量 57 升）以及短暂的热身和放松期。暴露于环境空气中时，用力呼气功能显着下降（P < 0.05），症状增加。在受控的 O3 暴露中，反应在 .gtoreq 时显着。 0.16ppm；随着 O3 浓度的增加，其严重程度也随之增加。在净化空气中休息 1 小时后，效果仅部分逆转。环境暴露产生的反应与相同浓度下单独使用 O3 产生的反应大致相同。在典型的中度环境氧化剂污染事件中，共存污染物似乎并未增强 O3 的刺激性。在剧烈运动期间需要高通风率时，O3 本身会产生呼吸道刺激，其浓度略高于基于健康的联邦[美国]环境空气质量标准 0.12 ppm O3。
Volunteer bicyclists (50) were exposed to purified air containing O3 at controlled concentrations of 0, 0.08, 0.16, 0.24 and 0.32 ppm, and to oxidant polluted ambient air (mean O3 concentration 0.15 ppm, mean total particulate concentration 295 .mu.g/m3) in surburban Los Angeles [California, USA]. Exposures (in random order, 14 days apart) involved 1 h of heavy continuous exercise (mean minute volume 57 l) plus brief warm up and cool down periods. Significant (P < 0.05) forced expiratory function decrements and symptom increases occurred in ambient air exposures. In controlled O3 exposures, responses were significant at .gtoreq. 0.16 ppm; their severity increased with increasing O3 concentration. Effects were only partially reversed after 1 h rest in purified air. Ambient exposures produced about the same response as O3 alone at the same concentration. Coexisting pollutants did not appear to enhance the irritancy of O3 in typical moderate ambient oxidant pollution episodes. O3 itself produced respiratory irritation at concentrations slightly above the health based federal [USA] ambient air quality standard of 0.12 ppm O3, at high ventilation rates required during heavy exercise.