JAK/STAT-dependent gene regulation by cytokines
JAK/STAT-dependent gene regulation by cytokines
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DOI：
10.1358/dnp.2005.18.4.908658
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发表时间：
2005-05-01
影响因子：
--
通讯作者：
Duschl, A
中科院分区：
文献类型：
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作者：
Hebenstreit, D;Horejs-Hoeck, J;Duschl, A
Janus激酶-信号转导子和转录激活子（Jak-STAT）通路是许多细胞因子信号转导的关键通路。Jak-STAT信号转导的失调与各种人类疾病有关。最近的研究有助于揭示一些调节机制，改变信号反应的数量和质量。在这里，我们总结了我们目前对Jak-STAT信号的了解。(c)2005年《科学》杂志。All rights reserved.
The Janus kinase-signal transducer and activator of transcription (Jak-STAT) pathway is essential for the signal transduction of many cytokines. Dysregulation of Jak-STAT signaling is associated with various human diseases. Recent studies have helped to shed some light on regulatory mechanisms that modify quantity and quality of the signaling response. Here, we summarize our current knowledge on Jak-STAT signaling. (c) 2005 Prous Science. All rights reserved.