Angiotensin-(1-7) for diabetic kidney disease: better than an angiotensin-converting enzyme inhibitor alone?

Angiotensin-(1-7) for diabetic kidney disease: better than an angiotensin-converting enzyme inhibitor alone?
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血管紧张素-(1-7)治疗糖尿病肾病:比单独使用血管紧张素转换酶抑制剂更好?

DOI:
10.1016/j.kint.2019.05.028
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发表时间:
2019
影响因子:
19.6
通讯作者:
Batlle,Daniel
Batlle,Daniel
中科院分区:
医学1区
文献类型:
--
作者:
Marquez,Alonso;Batlle,Daniel

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在这篇评论中,我们强调了Cassiset www.example.com描述的糖尿病肾病小鼠模型的环血管紧张素-(1 - 7)的肾保护作用。这项研究的重要性在于,这种肽甚至比单独给予血管紧张素转换酶抑制剂赖诺普利更具有保护作用,当这两种化合物联合使用时,肾脏保护作用是相加的。
In this commentary we emphasize the renoprotective effect of cyclic angiotensin-(1-7) described by Cassiset al.in a mouse model of diabetic kidney disease. The importance of the study is that this peptide was even more protective than the angiotensin-converting enzyme inhibitor lisinopril administered alone and that when the 2 componds were combined, the renoprotective action was additive.