Multi-photon and electron impact ionisation studies of reactivity in adenine-water clusters
Multi-photon and electron impact ionisation studies of reactivity in adenine-water clusters
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DOI：
10.1016/j.ijms.2014.01.007
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发表时间：
2014-05-15
影响因子：
1.8
通讯作者：
Eden, S.
中科院分区：
文献类型：
--
作者：
Barc, B.;Ryszka, M.;Eden, S.
多光子电离（MPI）和电子轰击电离（EH）质谱实验已经进行了探测单分子和分子间的反应性在水合腺嘌呤集群。首次研究了水分子团簇对腺嘌呤产生碎片离子的影响。虽然NH 4+片段的观察表明质子化腺嘌呤的解离，但主要的水合作用是增强C4 H4 N4+的产生和抑制具有高活化能的解离电离途径。这些观察结果可以归因于能量从激发的腺嘌呤自由基阳离子通过集群解离。MPI和EII测量的比较提供了第一个实验证据，支持次黄嘌呤形成腺嘌呤-水集群通过理论预测的无障碍脱氨基反应在封闭的壳复合物。(C)2014爱思唯尔有限公司版权所有。
Multi-photon ionisation (MPI) and electron impact ionisation (EH) mass spectrometry experiments have been carried out to probe unimolecular and intermolecular reactivities in hydrated adenine clusters. The effects of clustering with water on fragment ion production from adenine have been studied for the first time. While the observation of NH4+ fragments indicated the dissociation of protonated adenine, the dominant hydration effects were enhanced C4H4N4+ production and the suppression of dissociative ionisation pathways with high activation energies. These observations can be attributed to energy removal from the excited adenine radical cation via cluster dissociation. Comparisons of MPI and EII measurements provided the first experimental evidence supporting hypoxanthine formation in adenine-water clusters via theoretically predicted barrierless deamination reactions in closed shell complexes. (C) 2014 Elsevier B.V. All rights reserved.