Do you see what I feel? – Electrophysiological correlates of emotional face and body perception in schizophrenia

Do you see what I feel? – Electrophysiological correlates of emotional face and body perception in schizophrenia
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你明白我的感受吗?

DOI:
10.1016/j.clinph.2013.10.046
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发表时间:
2014
影响因子:
4.7
通讯作者:
Suchan B
Suchan B
中科院分区:
医学3区
文献类型:
--
作者:
Thoma P;Soria Bauser D;Norra C;Brüne M;Juckel G;Suchan B

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目的:我们的目的是阐明精神分裂症患者身体加工的类似缺陷是否与情感面部加工受损(行为上和关于P100和N170成分)相平行。此外,我们的目的是评估通过处理情绪或个人身份的刺激调节。方法采用延迟样本匹配任务对14例精神分裂症患者和15例健康对照者进行评估,该任务包括身体和面部的情绪(相同价与不同价)和个人同一性(同一人与不同人)的变化。结果患者整体行为表现较差。在对照组中,“相同身份/不同情绪”与“相同身份/相同情绪”条件下的P100波幅增强,不同情绪与相同情绪下的N170波幅更大。在这些患者中,面部的P100振幅在右半球相对于左半球增强,而身体的P100振幅则没有增强。结论精神分裂症患者对面孔和身体的情绪和个人同一性对P100和N170成分的调节存在缺陷,这可能与语境加工缺陷有关。意义:我们的研究结果首次提示精神分裂症患者身体加工的电生理相关改变。
ObjectiveWe aimed to elucidate whether impaired affective face processing – behaviourally and with regard to P100 and N170 components – is paralleled by similar deficits in body processing in schizophrenia. Furthermore, we aimed to assess modulations by the processing of emotional or personal identity of the stimuli.MethodsFourteen patients with schizophrenia and 15 healthy controls were assessed with a Delayed Matching-to-Sample Task involving variations of the emotional (same vs. different valence) and personal identity (same vs. different person) of bodies and faces.ResultsPatients showed overall poorer behavioural performance. In controls, P100 amplitudes were enhanced in the “same identity/different emotions” vs. “same identity/same emotion” condition and N170 amplitudes were larger for different vs. same emotions. In the patients, P100 amplitudes were enhanced in the right relative to the left hemisphere for faces, but not for bodies.ConclusionsPatients with schizophrenia show deficient modulation of the P100 and N170 components by emotional and personal identity of faces and bodies, which may relate to deficient context processing.SignificanceOur findings suggest for the first time alterations of the electrophysiological correlates of body processing in schizophrenia.
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