Validation of the sign and symptom check-list for persons with HIV disease (SSC-HIV)
Validation of the sign and symptom check-list for persons with HIV disease (SSC-HIV)
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DOI：
10.1046/j.1365-2648.1999.01204.x
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发表时间：
1999-11-01
影响因子：
3.8
通讯作者：
Inouye, J
中科院分区：
文献类型：
--
作者：
Holzemer, WL;Henry, SB;Inouye, J
艾滋病毒感染者的症状管理被认为是护理管理的一个极其重要的组成部分。本文报告了一种新的体征和症状评估工具的验证，该工具旨在使用两个HIV感染者样本（研究1：n = 247;研究2：n = 686）评估HIV相关症状的强度。研究I数据是在1994年至1996年开始高效抗逆转录病毒治疗（HAART）之前收集的。研究2的数据收集于1997年至1998年广泛采用HAART治疗后。艾滋病毒感染者体征和症状检查表（SSC-HIV）的最初版本包括41种体征和症状。将该量表提交至具有方差最大旋转的主成分因子分析。最终的解决方案报告了六个因素，解释了68.9%的方差。六个症状群（因子）、因子中的项目数和Cronbach α可靠性估计值为：不适/虚弱/疲劳（6项，α = 0.90）;困惑/痛苦（4项，α = 0.90）;发热/寒战（4项，α = 0.85）;胃肠道不适（4项，α = 0.81）;呼吸短促（3项，α = 0.79）;恶心/呕吐（3项，α = 0.77）。这六个因素具有较强的可靠性估计和稳定的因素结构，支持26项工具的结构效度。其他证据支持的规模，以及其敏感性随时间变化的同时有效性。SSC-HIV的最终版本是一个26项量表，可供临床医生和研究人员使用，以衡量患者对HIV相关体征和症状的自我报告。
Symptom management for persons living with HIV disease is recognized as an extremely important component of care management. This article reports the validation of a new sign and symptom assessment tool designed to assess the intensity of HIV-related symptoms using two samples (study 1: n = 247; study 2: n = 686) of people living with HIV disease. Study I data were collected between 1994 and 1996 before the initiation of highly active antiretroviral therapy (HAART). Study 2 data were collected between 1997 and 1998 after the wide adoption of HAART therapy. The initial version of the Sign and Symptom Check-List for Persons with HIV Disease (SSC-HIV) included 41 signs and symptoms. This scale was submitted to a principal components factor analysis with a varimax: rotation. The final solution reports six factors explaining 68.9% of the variance. The six symptom clusters (factors), the number of items in the factor, and the Cronbach alpha reliability estimates were: malaise/weakness/fatigue (six items, alpha = 0.90); confusion/distress (four items, alpha = 0.90); fever/chills (four items, alpha = 0.85); gastrointestinal discomfort (four items, alpha = 0.81); shortness of breath (three items, alpha = 0.79); and nausea/vomiting (three items, alpha = 0.77). These six factors have strong reliability estimates and a stable factor structure that supports the construct validity of the 26-item instrument. Additional evidence supports the concurrent validity of the scale as well as its sensitivity to change over time. The final version of the SSC-HIV is a 26-item scale available for use by clinicians and researchers to measure the patient's self-report of HIV-related signs and symptoms.