Neural correlates of age-related reduction in visual motion priming.
Neural correlates of age-related reduction in visual motion priming.
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DOI：
10.1080/13825580802348588
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发表时间：
2009-03
期刊：
影响因子：
--
通讯作者：
Parasuraman R
中科院分区：
文献类型：
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作者：
Jiang Y;Luo YJ;Parasuraman R
以前我们报道过，启动的视觉运动知觉是减少老年人相比，年轻的成年人。为了研究这种年龄相关效应的神经机制，在两个实验中记录了年轻人和老年人对运动方向的知觉判断过程中的事件相关脑电位（ERP）。当判断单步运动时，年轻人和老年人都引起了显着更大的ERP晚正成分（LPC）反应，明确的运动相比，LPC反应引起的模糊运动。相反，与年轻的成年人相比，老年人诱发可比的，但延迟ERP反应的单一运动步骤。在第二个实验中，年轻组和老年组判断两个连续运动步骤的方向（运动启动或运动反向）。在短（200-400 ms）刺激起始时间（SOA）条件下，年轻人对启动和反转条件的ERP反应差异显著大于老年人。本研究首次提供了脑老化导致早期视皮层对单个运动方向和视觉运动启动的延迟加工的电生理证据。当连续的运动信号在400 ms内被紧密地及时放置时，颞顶区神经反应的强度和时间特征的与运动相关的变化在老年人中特别明显。
Previously we reported that priming of visual motion perception is reduced in older adults compared to younger adults. To examine the neural mechanisms underlying this age-related effect, event-related brain potentials (ERPs) were recorded during perceptual judgments of motion directions by younger and older adults in two experiments. When judging single-step motion, both younger and older adults evoked significantly larger ERP late positive component (LPC) responses to unambiguous motion compared to LPC responses elicited by ambiguous motion. In contrast, compared to the younger adults, the older adults evoked comparable but delayed ERP responses to single motion steps. In the second experiment the younger and older groups judged the directions of two successive motion-steps (either motion priming or motion reversals). Under short (200–400 ms) stimulus onset asynchrony (SOA), the difference between the ERP responses to priming and reversal conditions was significantly larger for the younger than for the older adults. This study provides the first electrophysiological evidence that brain aging leads to delayed processing of single motion direction and visual motion priming as early as 100 ms in the early visual cortex. Age-related changes in strength and temporal characteristics of neural responses in temporal-parietal regions were particularly pronounced in older adults when successive motion signals are placed closely in time, within 400 ms.