Metal-Assisted and Microwave-Accelerated Evaporative Crystallization: Application to L-Alanine.

Metal-Assisted and Microwave-Accelerated Evaporative Crystallization: Application to L-Alanine.
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金属辅助和微波加速蒸发结晶:在 L-丙氨酸中的应用。

DOI:
10.1021/cg201018j
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发表时间:
2011
影响因子:
3.8
通讯作者:
Aslan,Kadir
Aslan,Kadir
中科院分区:
化学2区
文献类型:
--
作者:
Alabanza,AnginelleM;Aslan,Kadir

文献摘要

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L-丙氨酸是一种重要的氨基酸,在许多蛋白质的分子结构中起着关键作用。这种分子的结晶形式目前在化学、制药和食品工业中有很高的需求。然而,传统的蒸发结晶方法需要几个小时才能完成,并且并不总是一致地产生可用的晶体。使用金属辅助和微波加速蒸发结晶(MA-MAEC)技术,更大和更好的organizedl-丙氨酸晶体形成在一小部分的时间使用室温结晶。该技术可应用于氨基酸以外的有机分子,因此将能够生产当今工业所需的大量分子晶体。
l-Alanine is an important amino acid that plays a key role in the molecular structure of many proteins. Crystallized forms of this molecule are currently in high demand in chemical, pharmaceutics, and food industries. However, the traditional evaporative crystallization method takes up to several hours to complete and does not always consistently yield usable crystals. Using the metal-assisted and microwave-accelerated evaporative crystallization (MA-MAEC) technique, larger and better-organizedl-alanine crystals were formed in a fraction of the time using room temperature crystallization. This technique may be applicable to organic molecules other than amino acids and thus will be able to produce the large amount of molecular crystals desired by industries today.