Expression profiling of virulence and pathogenicity genes of Xanthomonas axonopodis pv. citri

Expression profiling of virulence and pathogenicity genes of Xanthomonas axonopodis pv. citri
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DOI:
10.1128/jb.187.3.1201-1205.2005
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发表时间:
2005-02-01
影响因子:
3.2
通讯作者:
Machado, MA
Machado, MA
中科院分区:
生物学3区
文献类型:
--
作者:
Astua-Monge, G;Freitas-Astua, J;Machado, MA

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应用基因芯片技术对日本番茄黄单胞菌致病变种279个基因进行了研究。与致病性和毒力潜在相关的citri用于比较该细菌响应于两种合成培养基的转录改变。数据分析表明,31个基因在合成培养基XVM 2中表达上调,只有7个基因被抑制。结果表明,XVM2可以作为一个体外系统,以确定候选基因参与X的发病机制。轴足虫变种柑橘。
DNA macroarrays of 279 genes of Xanthomonas axonopodis pv. citri potentially associated with pathogenicity and virulence were used to compare the transcriptional alterations of this bacterium in response to two synthetic media. Data analysis indicated that 31 genes were up-regulated by synthetic medium XVM2, while only 7 genes were repressed. The results suggest that XVM2 could be used as an in vitro system to identify candidate genes involved in pathogenesis of X. axonopodis pv. citri.