Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA
Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA
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DOI：
10.1007/s10334-019-00784-w
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发表时间：
2019-10-18
影响因子：
2.3
通讯作者：
Sourbron, Steven
中科院分区：
文献类型：
--
作者：
Mendichovszky, Iosif;Pullens, Pim;Sourbron, Steven
目的肾脏MRI生物标志物的潜力已越来越多地被认识到，但临床转化需要更多的标准化。PARENCHIMA共识项目旨在开发和应用一种生成肾脏MRI技术建议的流程。方法2018年7月成立了一个工作组，重点关注五种方法。达成共识的过程草案公开分发供磋商，并在公开会议上定稿（布拉格，2018年10月）。四个专家小组在2018年10月至2019年3月期间完成了调查，讨论了结果，并在面对面的会议（奥胡斯，2019年3月）上完善了调查，并完成了第二轮（2019年5月）。结果定义了一个七阶段的过程：（1）专家小组的形成;（2）使用环境的定义;（3）文献综述;（4）MRI方案的收集和比较;（5）通过近似德尔菲方法达成共识;（6）以供应商中立和供应商特定术语报告结果;（7）持续审查和更新。这一进程的实施产生了166项协商一致声明。结论：该过程在非常不同的MRI方法中产生了有意义的技术建议，同时允许随着未决问题的解决而改进和完善。该结果可能会得到肾脏MRI社区的广泛支持，从而促进更多的协调。
Purpose The potential of renal MRI biomarkers has been increasingly recognised, but clinical translation requires more standardisation. The PARENCHIMA consensus project aims to develop and apply a process for generating technical recommendations on renal MRI. Methods A task force was formed in July 2018 focused on five methods. A draft process for attaining consensus was distributed publicly for consultation and finalised at an open meeting (Prague, October 2018). Four expert panels completed surveys between October 2018 and March 2019, discussed results and refined the surveys at a face-to-face meeting (Aarhus, March 2019) and completed a second round (May 2019). Results A seven-stage process was defined: (1) formation of expert panels; (2) definition of the context of use; (3) literature review; (4) collection and comparison of MRI protocols; (5) consensus generation by an approximate Delphi method; (6) reporting of results in vendor-neutral and vendor-specific terms; (7) ongoing review and updating. Application of the process resulted in 166 consensus statements. Conclusion The process generated meaningful technical recommendations across very different MRI methods, while allowing for improvement and refinement as open issues are resolved. The results are likely to be widely supported by the renal MRI community and thereby promote more harmonisation.