Laser application in neurosurgery.
Laser application in neurosurgery.
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DOI：
10.4103/sni.sni_489_16
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发表时间：
2017
影响因子：
--
通讯作者：
Preul MC
中科院分区：
文献类型：
--
作者：
Belykh E;Yagmurlu K;Martirosyan NL;Lei T;Izadyyazdanabadi M;Malik KM;Byvaltsev VA;Nakaji P;Preul MC
基于受激辐射（激光）产生的光放大的技术创新已广泛用于神经外科领域。我们回顾了医学文献，以确定当前基于激光的技术在神经外科手术、诊断和治疗中的应用。文献中报道的激光技术的外科应用包括脑组织的经皮激光消融、在开放式和内窥镜下颅骨手术中使用外科激光、激光辅助显微吻合术和脑肿瘤的光动力治疗。激光系统还用于椎间盘退变治疗、用于经颅激光治疗和神经再生的激光能量的治疗应用以及基于激光的新型诊断技术（例如，激光扫描显微内镜和拉曼光谱学），用于病理组织的询问。尽管在使用激光治疗方面存在争议，但激光在微创手术中的应用显示出有希望的结果，值得进一步研究。基于激光的显微成像设备已经被开发和小型化，以用于术中快速病理诊断。激光用于神经外科和相关神经临床情况的多种方式证明了激光科学的技术进步和实用性。
Technological innovations based on light amplification created by stimulated emission of radiation (LASER) have been used extensively in the field of neurosurgery. We reviewed the medical literature to identify current laser-based technological applications for surgical, diagnostic, and therapeutic uses in neurosurgery. Surgical applications of laser technology reported in the literature include percutaneous laser ablation of brain tissue, the use of surgical lasers in open and endoscopic cranial surgeries, laser-assisted microanastomosis, and photodynamic therapy for brain tumors. Laser systems are also used for intervertebral disk degeneration treatment, therapeutic applications of laser energy for transcranial laser therapy and nerve regeneration, and novel diagnostic laser-based technologies (e.g., laser scanning endomicroscopy and Raman spectroscopy) that are used for interrogation of pathological tissue. Despite controversy over the use of lasers for treatment, the surgical application of lasers for minimally invasive procedures shows promising results and merits further investigation. Laser-based microscopy imaging devices have been developed and miniaturized to be used intraoperatively for rapid pathological diagnosis. The multitude of ways that lasers are used in neurosurgery and in related neuroclinical situations is a testament to the technological advancements and practicality of laser science.